STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FLIIProtein flightless-1 homolog isoform X1. (1247 aa)    
Predicted Functional Partners:
LRRFIP2
Leucine-rich repeat flightless-interacting protein 2 isoform X1.
    
 
 0.971
ADGRL2
Adhesion G protein-coupled receptor L2.
    
 
 0.822
ADGRL3
Adhesion G protein-coupled receptor L3.
    
 
 0.822
NTNG1
netrin-G1 isoform X1.
    
 0.723
CDC42SE1
CDC42 small effector protein 1.
      
 0.673
CDC42SE2
CDC42 small effector protein 2.
    
 
 0.656
CDC42BPB
Serine/threonine-protein kinase MRCK beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 0.627
CASK
Peripheral plasma membrane protein CASK isoform X1; Belongs to the MAGUK family.
    
  0.615
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.604
CDC42BPA
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 0.599
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.