STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKHD1Fibrocystin. (4076 aa)    
Predicted Functional Partners:
ENSEEUP00000000585
annotation not available
      
 0.769
PKD1
Polycystin-1 isoform X1.
      
 0.742
CBLB
Cbl proto-oncogene B.
    
 0.698
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.698
NEK8
Serine/threonine-protein kinase Nek8.
      
 0.680
ELF3
ETS-related transcription factor Elf-3.
      
 0.638
ARL13B
ADP-ribosylation factor-like protein 13B isoform X1.
      
 0.637
SSTR3
Somatostatin receptor type 3; Belongs to the G-protein coupled receptor 1 family.
     
 0.620
ENSEEUP00000007626
annotation not available
    
 0.618
PTK7
Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.607
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.