STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIRREL3Kin of IRRE-like protein 3. (760 aa)    
Predicted Functional Partners:
NPHS1
Nephrin.
   
0.992
CNTN5
Contactin-5.
    
 0.810
EFNA5
ephrin-A5 isoform X1; Belongs to the ephrin family.
      
 0.742
NTNG1
netrin-G1 isoform X1.
    
 0.723
NCK1
Cytoplasmic protein.
    
 0.680
NCK2
Cytoplasmic protein.
    
 0.680
CDH8
Cadherin-8; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.680
KCNG4
Potassium voltage-gated channel subfamily G member 4; Belongs to the potassium channel family.
    
 
 0.673
PPP4R4
Serine/threonine-protein phosphatase 4 regulatory subunit 4.
     
 0.668
TJP1
Tight junction protein ZO-1 isoform X4; Belongs to the MAGUK family.
    
 0.644
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.