STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JMJD6Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1. (414 aa)    
Predicted Functional Partners:
LOC103121078
Uncharacterized protein LOC103123889 isoform X1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.904
LOC103121078-5
Histone H4.
    
 0.904
BRD3
Bromodomain-containing protein 3 isoform X1.
    
 
 0.839
PTOV1
Prostate tumor-overexpressed gene 1 protein.
      
 0.727
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
      
 0.687
BRD2
Bromodomain-containing protein 2 isoform X1.
    
 
 0.673
LOC103115402
Putative RNA-binding protein Luc7-like 2 isoform X4.
   
 
 0.668
LOC103123893
Uncharacterized protein LOC103123927.
    
  0.647
LOC103123893-2
Histone H3.1.
    
  0.647
LOC103123893-3
Histone H3.1.
    
  0.647
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.