STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (994 aa)    
Predicted Functional Partners:
FLT3LG
Fms-related tyrosine kinase 3 ligand.
    
 0.988
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
    
 0.962
PDGFB
Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
   
 0.953
PDGFC
Platelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.944
ENSEEUP00000007255
annotation not available
    
 0.942
GRB2
Growth factor receptor bound protein 2.
    
 0.940
ENSEEUP00000003488
annotation not available
    
 0.939
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.938
VEGFB
Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family.
    
 0.935
ENSEEUP00000011861
annotation not available
   
 0.935
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.