STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL11ADP-ribosylation factor-like protein 11; Belongs to the small GTPase superfamily. Arf family. (190 aa)    
Predicted Functional Partners:
ENSEEUP00000010018
annotation not available
    
 0.935
ITSN1
Intersectin-1 isoform X3.
    
 0.900
GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X2.
    
 0.824
ARFGAP1
ADP-ribosylation factor GTPase-activating protein 1 isoform X2.
   
 0.816
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.803
ENSEEUP00000006207
annotation not available
   
 0.788
PI4KB
Phosphatidylinositol 4-kinase beta isoform X6; Belongs to the PI3/PI4-kinase family.
    
 0.787
LRRC15
Leucine-rich repeat-containing protein 15.
    
 0.782
AP1G2
AP-1 complex subunit gamma.
    
 0.778
TSGA13
Testis-specific gene 13 protein.
    
 0.767
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
Server load: low (28%) [HD]