RNF185 protein (Erinaceus europaeus) - STRING interaction network

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RNF185

E3 ubiquitin-protein ligase RNF185 isoform X1. (190 aa)

Predicted Functional Partners:

ERLIN2

0.926

RNF5

0.868

ENSEEUP00000003419

0.861

TMUB2

0.832

UBE2J1

0.809

ENSEEUP00000010619

0.790

RNF175

0.784

HERPUD2

0.768

CFTR

0.768

NPLOC4

0.746

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	ENSEEUP00000010619	ENSEEUP00000006000	ENSEEUP00000010619	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	annotation not available	0.884
CFTR	ERLIN2	ENSEEUP00000006000	ENSEEUP00000004708	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Erlin-2.	0.624
CFTR	RNF185	ENSEEUP00000006000	ENSEEUP00000008951	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	E3 ubiquitin-protein ligase RNF185 isoform X1.	0.768
CFTR	RNF5	ENSEEUP00000006000	ENSEEUP00000013063	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	E3 ubiquitin-protein ligase RNF5.	0.773
ENSEEUP00000003419	RNF185	ENSEEUP00000003419	ENSEEUP00000008951	annotation not available	E3 ubiquitin-protein ligase RNF185 isoform X1.	0.861
ENSEEUP00000010619	CFTR	ENSEEUP00000010619	ENSEEUP00000006000	annotation not available	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.884
ENSEEUP00000010619	ERLIN2	ENSEEUP00000010619	ENSEEUP00000004708	annotation not available	Erlin-2.	0.788
ENSEEUP00000010619	NPLOC4	ENSEEUP00000010619	ENSEEUP00000002549	annotation not available	Nuclear protein localization protein 4 homolog isoform X2.	0.924
ENSEEUP00000010619	RNF185	ENSEEUP00000010619	ENSEEUP00000008951	annotation not available	E3 ubiquitin-protein ligase RNF185 isoform X1.	0.790
ENSEEUP00000010619	RNF5	ENSEEUP00000010619	ENSEEUP00000013063	annotation not available	E3 ubiquitin-protein ligase RNF5.	0.854
ENSEEUP00000010619	UBE2J1	ENSEEUP00000010619	ENSEEUP00000003653	annotation not available	Ubiquitin-conjugating enzyme E2 J1.	0.709
ERLIN2	CFTR	ENSEEUP00000004708	ENSEEUP00000006000	Erlin-2.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.624
ERLIN2	ENSEEUP00000010619	ENSEEUP00000004708	ENSEEUP00000010619	Erlin-2.	annotation not available	0.788
ERLIN2	RNF185	ENSEEUP00000004708	ENSEEUP00000008951	Erlin-2.	E3 ubiquitin-protein ligase RNF185 isoform X1.	0.926
ERLIN2	RNF5	ENSEEUP00000004708	ENSEEUP00000013063	Erlin-2.	E3 ubiquitin-protein ligase RNF5.	0.886
ERLIN2	TMUB2	ENSEEUP00000004708	ENSEEUP00000008869	Erlin-2.	Transmembrane and ubiquitin-like domain-containing protein 2 isoform X2.	0.792
HERPUD2	NPLOC4	ENSEEUP00000005175	ENSEEUP00000002549	HERPUD family member 2.	Nuclear protein localization protein 4 homolog isoform X2.	0.403
HERPUD2	RNF185	ENSEEUP00000005175	ENSEEUP00000008951	HERPUD family member 2.	E3 ubiquitin-protein ligase RNF185 isoform X1.	0.768
HERPUD2	RNF5	ENSEEUP00000005175	ENSEEUP00000013063	HERPUD family member 2.	E3 ubiquitin-protein ligase RNF5.	0.600
HERPUD2	TMUB2	ENSEEUP00000005175	ENSEEUP00000008869	HERPUD family member 2.	Transmembrane and ubiquitin-like domain-containing protein 2 isoform X2.	0.701