STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMG1Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family. (3662 aa)    
Predicted Functional Partners:
SMG8
Protein SMG8.
   
 0.998
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 
 0.998
SMG7
Protein SMG7 isoform X4.
   
 0.993
RBM8A
RNA binding motif protein 8A.
    
 
 0.979
RPTOR
Regulatory-associated protein of mTOR isoform X1.
   
 0.976
RICTOR
Rapamycin-insensitive companion of mTOR isoform X2.
   
 0.974
MAPKAP1
Target of rapamycin complex 2 subunit MAPKAP1 isoform X1.
    
 0.969
EIF4A3
Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.
   
 
 0.963
RRAGC
Ras-related GTP-binding protein C isoform X1.
    
 0.956
ENSEEUP00000009992
annotation not available
    
 0.956
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.