STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (729 aa)    
Predicted Functional Partners:
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit isoform X1.
   
 0.999
GTF2H1
General transcription factor IIH subunit 1 isoform X1.
    
 0.999
MNAT1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.996
ENSEEUP00000010992
annotation not available
    
 0.995
GTF2E1
General transcription factor IIE subunit 1.
   
 0.994
ENSEEUP00000009190
annotation not available
    
 0.994
GTF2H3
General transcription factor IIH subunit 3.
    
 0.991
ENSEEUP00000008599
annotation not available
    
 0.991
LOC103116283
General transcription factor IIH subunit 3-like isoform X2.
    
 0.991
XPA
DNA repair protein complementing XP-A cells.
    
 0.984
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.