STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDFIP1NEDD4 family-interacting protein 1. (175 aa)    
Predicted Functional Partners:
NEDD4
E3 ubiquitin-protein ligase NEDD4.
    
 
 0.980
WWP2
E3 ubiquitin-protein ligase.
    
 
 0.880
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.860
SMURF2
E3 ubiquitin-protein ligase.
    
 
 0.760
SMURF1
E3 ubiquitin-protein ligase.
    
 
 0.735
NEDD4L
E3 ubiquitin-protein ligase NEDD4-like isoform X1.
    
 
 0.686
PRRG4
Transmembrane gamma-carboxyglutamic acid protein 4.
      
 0.671
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.619
SLC11A2
Natural resistance-associated macrophage protein 2 isoform X2.
   
 
 0.590
SLC11A1
Natural resistance-associated macrophage protein 1.
   
 
 0.590
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.