STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSPYL1Testis-specific Y-encoded-like protein 1; Belongs to the nucleosome assembly protein (NAP) family. (288 aa)    
Predicted Functional Partners:
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 
 0.794
ASF1A
Histone chaperone ASF1A.
   
 
 0.695
ANP32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B.
   
 0.663
ANP32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E.
   
 0.663
ENSEEUP00000005854
annotation not available
   
 0.663
TDRP
Testis development related protein.
      
 0.626
NUP214
Nuclear pore complex protein Nup214.
     
 0.617
ENO4
Enolase-like protein ENO4.
   
 
 0.570
TSPYL2
Testis-specific Y-encoded-like protein 2 isoform X3; Belongs to the nucleosome assembly protein (NAP) family.
  
 
  
0.567
LOC103121078
Uncharacterized protein LOC103123889 isoform X1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.544
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.