STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR2C2Nuclear receptor subfamily 2 group C member 2 isoform X2. (570 aa)    
Predicted Functional Partners:
JAZF1
Juxtaposed with another zinc finger protein 1.
    
 
 0.929
NCOR1
Nuclear receptor corepressor 1.
   
 0.773
ENSEEUP00000011122
annotation not available
   
 0.750
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.722
TADA1
Transcriptional adapter 1.
   
 0.685
TSC1
Hamartin isoform X2.
   
 0.665
ENSEEUP00000005213
annotation not available
    
 0.645
HSP90B1
Endoplasmin.
   
 0.631
TRAP1
Heat shock protein 75 kDa, mitochondrial.
   
 0.624
EP300
Histone acetyltransferase p300.
   
 0.611
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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