STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDZK1IP1PDZK1 interacting protein 1. (113 aa)    
Predicted Functional Partners:
SLC5A2
Solute carrier family 5 member 2.
    
 
 0.834
TMEM223
Transmembrane protein 223.
      
 0.765
PDZK1
Na(+)/H(+) exchange regulatory cofactor NHE-RF3.
    
 
 0.693
RNF6
E3 ubiquitin-protein ligase RNF6 isoform X1.
      
 0.635
PKD2L1
Polycystic kidney disease 2-like 1 protein.
      
 0.586
ENSEEUP00000000135
annotation not available
    
   0.573
SLC5A9
Sodium/glucose cotransporter 4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
    
   0.573
PCDH9
Protocadherin-9.
      
 0.531
FAM111A
Protein FAM111A.
      
 0.530
SLC5A3
Sodium/myo-inositol cotransporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
    
   0.491
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.