STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1592 aa)    
Predicted Functional Partners:
ENSEEUP00000011333
annotation not available
    
 0.983
UNC79
Protein unc-79 homolog isoform X2.
   
 0.982
ENSEEUP00000001326
annotation not available
    
 0.937
SCN2B
Sodium channel subunit beta-2.
   
 0.911
ENSEEUP00000012683
annotation not available
  
 
 
0.895
CAMK2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2; Belongs to the protein kinase superfamily.
    
 0.872
CAMK2D
Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6; Belongs to the protein kinase superfamily.
    
 0.872
ENSEEUP00000001134
annotation not available
    
 0.843
SCN3B
Sodium channel subunit beta-3.
    
 0.839
ENSEEUP00000009319
annotation not available
   
 0.768
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.