STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF11Tumor necrosis factor ligand superfamily member. (244 aa)    
Predicted Functional Partners:
TNFRSF11B
Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
    
 0.995
TNFRSF11A
Tumor necrosis factor receptor superfamily member 11A.
    
 0.995
CD40
Tumor necrosis factor receptor superfamily member 5.
   
 0.886
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
      
 0.793
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.704
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
     
0.703
TNFRSF1B
Tumor necrosis factor receptor superfamily member 1B.
   
 
 0.686
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
     
 0.659
TNFRSF13C
Tumor necrosis factor receptor superfamily member 13C.
   
 
 0.638
MAP3K14
Mitogen-activated protein kinase kinase kinase 14-like.
   
 
 0.633
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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