STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2D3CSH2 domain-containing protein 3C isoform X1. (860 aa)    
Predicted Functional Partners:
BCAR1
Breast cancer anti-estrogen resistance protein 1.
    
 0.938
LMBR1L
Protein LMBR1L isoform X1; Belongs to the LIMR family.
      
 0.794
FBXL20
F-box/LRR-repeat protein 20 isoform X3.
     
 0.777
SEC24A
Protein transport protein Sec24A isoform X2.
    
 0.722
NEDD9
Enhancer of filamentation 1.
    
 0.648
HEG1
Protein HEG homolog 1 isoform X1.
   
 0.625
NKPD1
NTPase KAP family P-loop domain-containing protein 1.
    
 0.598
TEAD3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
    
 
 0.593
ENSEEUP00000009128
annotation not available
   
 0.592
LRGUK
Leucine-rich repeat and guanylate kinase domain-containing protein.
    
  0.591
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.