COMMD9 protein (Erinaceus europaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

COMMD9

COMM domain-containing protein 9. (198 aa)

Predicted Functional Partners:

COMMD6

0.991

COMMD2

0.971

COMMD10

0.971

ENSEEUP00000010507

0.969

COMMD5

0.967

COMMD1

0.955

COMMD8

0.908

CCDC93

0.897

VPS29

0.826

VPS35L

0.771

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC93	COMMD1	ENSEEUP00000014426	ENSEEUP00000013860	Coiled-coil domain-containing protein 93.	COMM domain-containing protein 1 isoform X1.	0.948
CCDC93	COMMD10	ENSEEUP00000014426	ENSEEUP00000000779	Coiled-coil domain-containing protein 93.	COMM domain-containing protein 10.	0.913
CCDC93	COMMD2	ENSEEUP00000014426	ENSEEUP00000000371	Coiled-coil domain-containing protein 93.	COMM domain containing 2.	0.859
CCDC93	COMMD5	ENSEEUP00000014426	ENSEEUP00000013237	Coiled-coil domain-containing protein 93.	COMM domain-containing protein 5.	0.894
CCDC93	COMMD6	ENSEEUP00000014426	ENSEEUP00000005510	Coiled-coil domain-containing protein 93.	COMM domain-containing protein 6 isoform X1.	0.924
CCDC93	COMMD8	ENSEEUP00000014426	ENSEEUP00000013647	Coiled-coil domain-containing protein 93.	COMM domain-containing protein 8.	0.877
CCDC93	COMMD9	ENSEEUP00000014426	ENSEEUP00000011583	Coiled-coil domain-containing protein 93.	COMM domain-containing protein 9.	0.897
CCDC93	ENSEEUP00000010507	ENSEEUP00000014426	ENSEEUP00000010507	Coiled-coil domain-containing protein 93.	annotation not available	0.987
CCDC93	VPS29	ENSEEUP00000014426	ENSEEUP00000004125	Coiled-coil domain-containing protein 93.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.909
CCDC93	VPS35L	ENSEEUP00000014426	ENSEEUP00000007549	Coiled-coil domain-containing protein 93.	UPF0505 protein C16orf62 homolog.	0.839
COMMD1	CCDC93	ENSEEUP00000013860	ENSEEUP00000014426	COMM domain-containing protein 1 isoform X1.	Coiled-coil domain-containing protein 93.	0.948
COMMD1	COMMD10	ENSEEUP00000013860	ENSEEUP00000000779	COMM domain-containing protein 1 isoform X1.	COMM domain-containing protein 10.	0.961
COMMD1	COMMD2	ENSEEUP00000013860	ENSEEUP00000000371	COMM domain-containing protein 1 isoform X1.	COMM domain containing 2.	0.959
COMMD1	COMMD5	ENSEEUP00000013860	ENSEEUP00000013237	COMM domain-containing protein 1 isoform X1.	COMM domain-containing protein 5.	0.939
COMMD1	COMMD6	ENSEEUP00000013860	ENSEEUP00000005510	COMM domain-containing protein 1 isoform X1.	COMM domain-containing protein 6 isoform X1.	0.978
COMMD1	COMMD8	ENSEEUP00000013860	ENSEEUP00000013647	COMM domain-containing protein 1 isoform X1.	COMM domain-containing protein 8.	0.942
COMMD1	COMMD9	ENSEEUP00000013860	ENSEEUP00000011583	COMM domain-containing protein 1 isoform X1.	COMM domain-containing protein 9.	0.955
COMMD1	ENSEEUP00000010507	ENSEEUP00000013860	ENSEEUP00000010507	COMM domain-containing protein 1 isoform X1.	annotation not available	0.982
COMMD1	VPS29	ENSEEUP00000013860	ENSEEUP00000004125	COMM domain-containing protein 1 isoform X1.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.778
COMMD1	VPS35L	ENSEEUP00000013860	ENSEEUP00000007549	COMM domain-containing protein 1 isoform X1.	UPF0505 protein C16orf62 homolog.	0.880