STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARK7Protein deglycase DJ-1. (106 aa)    
Predicted Functional Partners:
SOD1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
  
 0.980
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.930
CAT
Catalase.
  
 0.919
TMEM189-UBE2V1
Transmembrane protein 189 isoform X1.
   
 
  0.916
PINK1
Serine/threonine-protein kinase PINK1, mitochondrial.
    
 
 0.915
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 
 0.911
NFE2L2
Nuclear factor erythroid 2-related factor 2 isoform X1.
     
 0.906
BCL2L1
Bcl-2-like protein 1 isoform X1.
    
 0.900
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.848
GLOD4
Glyoxalase domain-containing protein 4.
  
 
 0.831
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.