STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSEEUP00000012389annotation not available (297 aa)    
Predicted Functional Partners:
REXO2
Oligoribonuclease, mitochondrial.
  
 0.908
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
    
 0.907
PCNA
Proliferating cell nuclear antigen.
  
 0.866
REXO5
Putative RNA exonuclease NEF-sp.
     
 0.854
PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial.
  
 
 0.747
HELZ2
Helicase with zinc finger domain 2 isoform X1.
   
 0.714
FBH1
F-box DNA helicase 1 isoform X1.
  
 
 0.683
DIS3
Exosome complex exonuclease RRP44 isoform X1; Belongs to the RNR ribonuclease family.
  
 0.681
GMPS
GMP synthase [glutamine-hydrolyzing] isoform X1.
  
 
 0.680
RPL36AL
60S ribosomal protein L36a-like isoform X2; Belongs to the eukaryotic ribosomal protein eL42 family.
     
 0.678
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.