STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSEEUP00000012422annotation not available (310 aa)    
Predicted Functional Partners:
TSC1
Hamartin isoform X2.
   
 0.922
TRAP1
Heat shock protein 75 kDa, mitochondrial.
   
 0.922
ENSEEUP00000004581
annotation not available
   
 0.901
HSP90B1
Endoplasmin.
   
 0.896
ENSEEUP00000014108
annotation not available
   
 0.882
PFDN4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.
      
 0.716
POLR3C
RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.656
AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1.
   
 
 0.637
AHSA2
Activator of 90 kDa heat shock protein ATPase homolog 2.
   
 
 0.637
HSPH1
Heat shock protein family H (Hsp110) member 1.
   
 
 0.621
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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