STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGNCingulin. (1085 aa)    
Predicted Functional Partners:
TJP1
Tight junction protein ZO-1 isoform X4; Belongs to the MAGUK family.
   
 
 0.924
ARHGEF2
Rho guanine nucleotide exchange factor 2.
     
 0.909
F11R
Junctional adhesion molecule A.
     
 0.893
TJP2
Tight junction protein ZO-2.
   
 
 0.779
TJP3
Tight junction protein ZO-3; Belongs to the MAGUK family.
   
 
 0.776
LOC103118223
A-kinase anchor protein 13-like.
     
 0.676
LOC107523107
Rho guanine nucleotide exchange factor 28-like.
     
 0.676
ARHGEF1
Rho guanine nucleotide exchange factor 1.
     
 0.532
ARHGEF11
Rho guanine nucleotide exchange factor 11 isoform X3.
     
 0.532
ARHGEF12
Rho guanine nucleotide exchange factor 12-like.
     
 0.532
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.