STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103124360Histone H3; Belongs to the histone H3 family. (136 aa)    
Predicted Functional Partners:
ENSEEUP00000005030
annotation not available
    
 0.927
KDM6A
Lysine-specific demethylase 6A isoform X4.
   
 0.922
ENSEEUP00000013778
annotation not available
   
 0.922
LOC103121078
Uncharacterized protein LOC103123889 isoform X1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.874
LOC103121078-5
Histone H4.
 
 
 0.874
ARID4A
AT-rich interactive domain-containing protein 4A.
   
 0.851
ARID4B
AT-rich interactive domain-containing protein 4B.
   
 0.851
H2AZ2
Histone H2A; Belongs to the histone H2A family.
 
 
 0.802
EZH1
Histone-lysine N-methyltransferase EZH2 isoform X4.
   
 0.796
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 0.767
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.