STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB14Growth factor receptor-bound protein 14 isoform X1. (476 aa)    
Predicted Functional Partners:
IGF1R
Tyrosine-protein kinase receptor.
    
 0.934
FGFR1
Fibroblast growth factor receptor.
    
 0.791
INSRR
Tyrosine-protein kinase receptor.
    
 0.787
SREBF1
Sterol regulatory element-binding protein 1 isoform X3.
      
 0.768
TEK
Angiopoietin-1 receptor.
   
  0.747
CRK
Adapter molecule crk isoform X1.
    
 0.739
GRB2
Growth factor receptor bound protein 2.
    
 0.735
INSIG2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
      
 0.720
PERP
P53 apoptosis effector related to PMP-22.
      
 0.720
MST1R
Macrophage-stimulating protein receptor.
   
 0.715
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.