STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NONOnon-POU domain-containing octamer-binding protein isoform X2. (468 aa)    
Predicted Functional Partners:
PSPC1
Paraspeckle component 1.
  
   
0.769
FUS
RNA-binding protein FUS isoform X1.
   
 
 0.759
ENSEEUP00000001770
annotation not available
   
 
 0.730
MATR3
Matrin-3 isoform X3.
   
 
 0.723
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 
 0.693
PRCC
Proline-rich protein PRCC isoform X1.
      
 0.638
HNRNPA2B1
Heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1.
   
 
 0.598
CPSF6
Cleavage and polyadenylation specificity factor subunit 6 isoform X1.
   
 
 0.598
HNRNPK
Heterogeneous nuclear ribonucleoprotein K isoform X1.
   
 
 0.590
ALYREF
THO complex subunit 4.
   
 
 0.580
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.