STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (922 aa)    
Predicted Functional Partners:
LLGL1
Lethal(2) giant larvae protein homolog 1 isoform X1.
    
 0.941
LLGL2
Lethal(2) giant larvae protein homolog 2.
    
 0.941
DLG3
Disks large homolog 3 isoform X1; Belongs to the MAGUK family.
  
 
0.938
HPCAL1
Hippocalcin like 1.
    
  0.924
CASK
Peripheral plasma membrane protein CASK isoform X1; Belongs to the MAGUK family.
   
 0.919
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.912
SCRIB
Protein scribble homolog isoform X1.
    
0.906
MAPK12
Mitogen-activated protein kinase.
    
 0.905
MAPK13
Mitogen-activated protein kinase.
    
  0.884
TJAP1
Tight junction-associated protein 1 isoform X2.
    
 0.882
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.