STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDLIM4PDZ and LIM domain protein 4 isoform X1. (332 aa)    
Predicted Functional Partners:
PTK2B
Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.728
PTK2
Focal adhesion kinase 1 isoform X5; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.728
GIT2
ARF GTPase-activating protein GIT2 isoform X1.
    
 0.712
GIT1
ARF GTPase-activating protein GIT1 isoform X1.
    
 0.712
CRK
Adapter molecule crk isoform X1.
    
 0.653
PRSS23
Serine protease 23.
      
 0.634
LIMK2
LIM domain kinase 2 isoform X3.
    
 0.634
ILK
Integrin-linked protein kinase isoform X1.
   
 0.619
CTNNA3
Catenin alpha-3.
   
 0.612
CTNNA1
Catenin alpha-1 isoform X1.
   
 0.612
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.