STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (889 aa)    
Predicted Functional Partners:
MAPK12
Mitogen-activated protein kinase.
    
 0.951
KRTCAP3
Keratinocyte associated protein 3.
      
 0.768
GRB2
Growth factor receptor bound protein 2.
    
 0.708
EPS15
Epidermal growth factor receptor substrate 15 isoform X1.
    
  0.682
MAPK14
Mitogen-activated protein kinase.
    
 0.672
ENSEEUP00000009203
annotation not available
    
 0.672
MAPK13
Mitogen-activated protein kinase.
    
 0.672
USP43
Ubiquitin carboxyl-terminal hydrolase 43 isoform X1; Belongs to the peptidase C19 family.
    
 
 0.642
RASAL1
rasGAP-activating-like protein 1 isoform X4.
    
 
 0.642
ENSEEUP00000014290
annotation not available
    
 0.637
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.