STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SESTD1SEC14 domain and spectrin repeat-containing protein 1. (698 aa)    
Predicted Functional Partners:
DACT1
Dapper homolog 1 isoform X1.
    
 
 0.674
DCC
DCC netrin 1 receptor.
    
 0.562
NEO1
Neogenin.
    
 0.562
LRRC17
Leucine-rich repeat-containing protein 17.
      
 0.547
RAP2C
Ras-related protein Rap-2c.
    
 0.542
ZSWIM2
E3 ubiquitin-protein ligase ZSWIM2.
      
 0.531
NUS1
Dehydrodolichyl diphosphate syntase complex subunit NUS1.
      
 0.530
RND2
Rho-related GTP-binding protein RhoN.
    
 0.526
RHOU
Ras homolog family member U.
    
 0.526
RND3
LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoE.
    
 0.526
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.