STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRM5Metabotropic glutamate receptor 5. (1189 aa)    
Predicted Functional Partners:
CAMK2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X4.
    
 0.900
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
  0.891
GNA14
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.885
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.885
GNA13
Guanine nucleotide-binding protein subunit alpha-13 isoform X3.
    
  0.885
ENSEEUP00000010586
annotation not available
   
 
 0.880
CAMK2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2; Belongs to the protein kinase superfamily.
   
 0.878
CAMK2D
Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6; Belongs to the protein kinase superfamily.
   
 0.878
AVP
Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family.
   
 
  0.865
GRM1
Metabotropic glutamate receptor 1.
  
  
 
0.865
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.