SDB18706.1 protein (Belnapia rosea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SDB18706.1

Dimethylhistidine N-methyltransferase. (318 aa)

Predicted Functional Partners:

SDB18694.1

0.999

SDB71917.1

0.815

SDB18719.1

0.773

SDB73065.1

0.499

SDB74858.1

0.499

SDB18665.1

0.487

SDB18680.1

0.487

SDB18729.1

0.485

SDB18738.1

0.485

SDB60098.1

0.477

Your Current Organism:

Belnapia rosea

NCBI taxonomy Id: 938405
Other names: B. rosea, Belnapia rosea Jin et al. 2012, Belnapia sp. CPCC 100156, CGMCC 1.10758, CPCC 100156, DSM 23312

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDB18665.1	SDB18680.1	SAMN02927895_00701	SAMN02927895_00702	Predicted methyltransferase, contains TPR repeat.	Glycosyl transferase family 41.	0.879
SDB18665.1	SDB18694.1	SAMN02927895_00701	SAMN02927895_00703	Predicted methyltransferase, contains TPR repeat.	Ergothioneine biosynthesis protein EgtB.	0.489
SDB18665.1	SDB18706.1	SAMN02927895_00701	SAMN02927895_00704	Predicted methyltransferase, contains TPR repeat.	Dimethylhistidine N-methyltransferase.	0.487
SDB18665.1	SDB18719.1	SAMN02927895_00701	SAMN02927895_00705	Predicted methyltransferase, contains TPR repeat.	Glycerophosphoryl diester phosphodiesterase.	0.507
SDB18665.1	SDB18729.1	SAMN02927895_00701	SAMN02927895_00706	Predicted methyltransferase, contains TPR repeat.	Branched-chain amino acid transport system ATP-binding protein.	0.436
SDB18680.1	SDB18665.1	SAMN02927895_00702	SAMN02927895_00701	Glycosyl transferase family 41.	Predicted methyltransferase, contains TPR repeat.	0.879
SDB18680.1	SDB18694.1	SAMN02927895_00702	SAMN02927895_00703	Glycosyl transferase family 41.	Ergothioneine biosynthesis protein EgtB.	0.487
SDB18680.1	SDB18706.1	SAMN02927895_00702	SAMN02927895_00704	Glycosyl transferase family 41.	Dimethylhistidine N-methyltransferase.	0.487
SDB18680.1	SDB18719.1	SAMN02927895_00702	SAMN02927895_00705	Glycosyl transferase family 41.	Glycerophosphoryl diester phosphodiesterase.	0.487
SDB18694.1	SDB18665.1	SAMN02927895_00703	SAMN02927895_00701	Ergothioneine biosynthesis protein EgtB.	Predicted methyltransferase, contains TPR repeat.	0.489
SDB18694.1	SDB18680.1	SAMN02927895_00703	SAMN02927895_00702	Ergothioneine biosynthesis protein EgtB.	Glycosyl transferase family 41.	0.487
SDB18694.1	SDB18706.1	SAMN02927895_00703	SAMN02927895_00704	Ergothioneine biosynthesis protein EgtB.	Dimethylhistidine N-methyltransferase.	0.999
SDB18694.1	SDB18719.1	SAMN02927895_00703	SAMN02927895_00705	Ergothioneine biosynthesis protein EgtB.	Glycerophosphoryl diester phosphodiesterase.	0.773
SDB18694.1	SDB18729.1	SAMN02927895_00703	SAMN02927895_00706	Ergothioneine biosynthesis protein EgtB.	Branched-chain amino acid transport system ATP-binding protein.	0.485
SDB18694.1	SDB18738.1	SAMN02927895_00703	SAMN02927895_00707	Ergothioneine biosynthesis protein EgtB.	Branched-chain amino acid transport system ATP-binding protein.	0.485
SDB18694.1	SDB71917.1	SAMN02927895_00703	SAMN02927895_04234	Ergothioneine biosynthesis protein EgtB.	Glutamine amidotransferase.	0.730
SDB18706.1	SDB18665.1	SAMN02927895_00704	SAMN02927895_00701	Dimethylhistidine N-methyltransferase.	Predicted methyltransferase, contains TPR repeat.	0.487
SDB18706.1	SDB18680.1	SAMN02927895_00704	SAMN02927895_00702	Dimethylhistidine N-methyltransferase.	Glycosyl transferase family 41.	0.487
SDB18706.1	SDB18694.1	SAMN02927895_00704	SAMN02927895_00703	Dimethylhistidine N-methyltransferase.	Ergothioneine biosynthesis protein EgtB.	0.999
SDB18706.1	SDB18719.1	SAMN02927895_00704	SAMN02927895_00705	Dimethylhistidine N-methyltransferase.	Glycerophosphoryl diester phosphodiesterase.	0.773

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.818

expected number of edges:

20

PPI enrichment p-value:

0.0113

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019470

4-hydroxyproline catabolic process

2 of 2

2.56

1.03

0.0133

GO:0046653

Tetrahydrofolate metabolic process

3 of 18

1.78

0.95

0.0133

GO:1901606

Alpha-amino acid catabolic process

3 of 28

1.59

0.9

0.0133

GO:0006575

Cellular modified amino acid metabolic process

5 of 102

1.25

0.87

0.0067

GO:0046416

D-amino acid metabolic process

2 of 6

2.08

0.87

0.0231

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008115

Sarcosine oxidase activity

3 of 9

2.08

1.58

0.00085

GO:0016645

Oxidoreductase activity, acting on the CH-NH group of donors

4 of 33

1.64

1.42

0.00074

GO:0016491

Oxidoreductase activity

9 of 515

0.8

0.69

0.00034

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1927

GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1, and Sarcosine oxidase, delta subunit family

4 of 24

1.78

1.79

0.00013

CL:1922

Mixed, incl. GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1, and NADH:flavin oxidoreductase / NADH oxidase family

5 of 50

1.56

1.63

0.00011

CL:1929

FAD dependent oxidoreductase central domain, and Sarcosine oxidase activity

3 of 18

1.78

1.3

0.0022

CL:1699

Mixed, incl. Carbon metabolism, and Oxidoreductase activity, acting on the CH-NH group of donors

7 of 181

1.15

0.00011

CL:5479

Mixed, incl. Alkylhydroperoxidase AhpD core, and EF-hand, calcium binding motif

2 of 6

2.08

0.92

0.0187

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00472

D-Arginine and D-ornithine metabolism

2 of 3

2.39

1.17

0.0071

map00330

Arginine and proline metabolism

3 of 57

1.28

0.73

0.0203

map01100

Metabolic pathways

11 of 1641

0.39

0.31

0.0071

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

10 of 1255

0.46

0.34

0.0135

GOCC:0005622

Intracellular

11 of 1613

0.39

0.3

0.0135

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF07992

Pyridine nucleotide-disulphide oxidoreductase

4 of 16

1.96

1.99

8.26e-05

PF13510

2Fe-2S iron-sulfur cluster binding domain

3 of 7

2.19

1.71

0.00052

PF04324

BFD-like [2Fe-2S] binding domain

2 of 2

2.56

1.27

0.0047

PF08669

Glycine cleavage T-protein C-terminal barrel domain

3 of 19

1.76

1.19

0.0038

PF01571

Aminomethyltransferase folate-binding domain

3 of 18

1.78

1.19

0.0038

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR041117

SoxA, A3 domain

5 of 5

2.56

4.02

1.96e-08

IPR041854

BFD-like [2Fe-2S]-binding domain superfamily

4 of 4

2.56

3.17

1.04e-06

IPR036188

FAD/NAD(P)-binding domain superfamily

7 of 80

1.5

2.15

3.98e-07

IPR042204

2Fe-2S iron-sulfur cluster binding domain, N-terminal

3 of 5

2.34

1.91

0.00025

IPR023753

FAD/NAD(P)-binding domain

4 of 24

1.78

1.7

0.00022

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (14%) [HD]

Permalink

Network

Neighborhood

Databases

Fusion

Textmining

Cooccurrence

Experiments

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About