STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC3SHC-transforming protein 3 isoform X1. (628 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-binding protein 2.
   
 0.992
EGFR
Epidermal growth factor receptor isoform X1.
    
 0.971
ERBB2
Receptor tyrosine-protein kinase erbB-2.
    
 0.971
ERBB4
Receptor tyrosine-protein kinase erbB-4 isoform X2.
    
 0.971
INSR
Insulin receptor isoform X1.
    
 0.962
SHC2
SHC-transforming protein 2 isoform X1.
  
 
 
0.925
PTK2
Focal adhesion kinase 1 isoform X1.
    
 0.920
SHC1
SHC-transforming protein 1 isoform X1.
     
0.916
MET
Proto-oncogene tyrosine-protein kinase Met.
   
 0.895
IGF1R
Insulin-like growth factor 1 receptor precursor.
    
 0.875
Your Current Organism:
Coturnix japonica
NCBI taxonomy Id: 93934
Other names: C. japonica, Coturnix coturnix Japonicus, Coturnix coturnix japanica, Coturnix coturnix japonica, Coturnix japonica japonica, Japanese quail
Server load: low (14%) [HD]