node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MPTP_0762 | cinA | MPTP_0762 | MPTP_0291 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.554 |
MPTP_0762 | ligA | MPTP_0762 | MPTP_0661 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.426 |
MPTP_0762 | mfd | MPTP_0762 | MPTP_0265 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.560 |
MPTP_0762 | mutM | MPTP_0762 | MPTP_1618 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.414 |
MPTP_0762 | recA | MPTP_0762 | MPTP_0292 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.708 |
MPTP_0762 | ruvA | MPTP_0762 | MPTP_0299 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.636 |
MPTP_0762 | ruvB | MPTP_0762 | MPTP_0300 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.497 |
MPTP_1250 | aspS | MPTP_1250 | MPTP_1372 | Late competence protein ComEC, DNA transport. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.450 |
MPTP_1250 | cinA | MPTP_1250 | MPTP_0291 | Late competence protein ComEC, DNA transport. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.651 |
MPTP_1250 | recA | MPTP_1250 | MPTP_0292 | Late competence protein ComEC, DNA transport. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.559 |
MPTP_1250 | ruvA | MPTP_1250 | MPTP_0299 | Late competence protein ComEC, DNA transport. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.640 |
MPTP_1250 | ruvB | MPTP_1250 | MPTP_0300 | Late competence protein ComEC, DNA transport. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.513 |
aspS | MPTP_1250 | MPTP_1372 | MPTP_1250 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Late competence protein ComEC, DNA transport. | 0.450 |
aspS | cinA | MPTP_1372 | MPTP_0291 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.456 |
aspS | ruvA | MPTP_1372 | MPTP_0299 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.641 |
cinA | MPTP_0762 | MPTP_0291 | MPTP_0762 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.554 |
cinA | MPTP_1250 | MPTP_0291 | MPTP_1250 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | Late competence protein ComEC, DNA transport. | 0.651 |
cinA | aspS | MPTP_0291 | MPTP_1372 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.456 |
cinA | recA | MPTP_0291 | MPTP_0292 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.879 |
cinA | ruvA | MPTP_0291 | MPTP_0299 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.552 |