STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDNuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (379 aa)    
Predicted Functional Partners:
MPTP_0860
Exonuclease SbcC.
 
 0.995
MPTP_0859
Exonuclease SbcC.
 
 0.990
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.984
MPTP_0861
Snf2 family protein.
  
 
 0.923
dinG
DinG family ATP-dependent helicase YoaA; 3'-5' exonuclease.
  
 0.746
MPTP_1260
ATP-dependent DNA helicase RecQ.
  
 0.677
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.673
MPTP_0390
Proline reductase proprotein, two subunits.
   
 0.587
MPTP_0660
ATP-dependent DNA helicase UvrD/PcrA.
   
 
 0.561
MPTP_0616
DNA polymerase III delta prime subunit.
  
 0.535
Your Current Organism:
Melissococcus plutonius
NCBI taxonomy Id: 940190
Other names: M. plutonius ATCC 35311, Melissococcus plutonius ATCC 35311, Melissococcus plutonius NCDO 2443, Melissococcus plutonius str. ATCC 35311, Melissococcus plutonius strain ATCC 35311
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.