STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPTP_1030Glycerophosphoryl diester phosphodiesterase. (551 aa)    
Predicted Functional Partners:
MPTP_1029
Hypothetical protein.
       0.709
MPTP_0924
Phosphate transport system permease protein PstA (TC 3.A.1.7.1).
  
  
 0.581
MPTP_0693
Alcohol dehydrogenase/ acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.554
dltC
D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
   
 0.528
MPTP_0969
Transcriptional regulator, Cro/CI family.
 
     0.525
MPTP_0125
CDP-diacylglycerol--glycerol-3-phosphate3- phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.521
mprF-2
Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
   
 0.504
MPTP_0921
Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
     
 0.500
MPTP_0631
Poly(glycerophosphate chain) D-alanine transfer protein DltD.
  
     0.490
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.470
Your Current Organism:
Melissococcus plutonius
NCBI taxonomy Id: 940190
Other names: M. plutonius ATCC 35311, Melissococcus plutonius ATCC 35311, Melissococcus plutonius NCDO 2443, Melissococcus plutonius str. ATCC 35311, Melissococcus plutonius strain ATCC 35311
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