STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPTP_1193Pyruvate oxidase; Belongs to the TPP enzyme family. (573 aa)    
Predicted Functional Partners:
MPTP_0833
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.975
MPTP_1340
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.954
MPTP_0728
Phosphate acetyltransferase.
  
 
 0.938
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.936
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.935
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.927
MPTP_0946
Pyruvate dehydrogenase E1 component betasubunit.
  
 
 0.925
MPTP_0169
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.920
MPTP_0203
Pyruvate formate-lyase.
     
 0.912
MPTP_1111
Pyruvate formate-lyase.
     
 0.912
Your Current Organism:
Melissococcus plutonius
NCBI taxonomy Id: 940190
Other names: M. plutonius ATCC 35311, Melissococcus plutonius ATCC 35311, Melissococcus plutonius NCDO 2443, Melissococcus plutonius str. ATCC 35311, Melissococcus plutonius strain ATCC 35311
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