STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPTP_1603Pyruvate decarboxylase, alpha-keto-acid decarboxylase. (556 aa)    
Predicted Functional Partners:
MPTP_0096
Alcohol dehydrogenase.
 
 
 
 0.767
MPTP_0693
Alcohol dehydrogenase/ acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.767
MPTP_1598
Alcohol dehydrogenase.
   
 
 0.529
MPTP_1206
Fructose-bisphosphate aldolase class II.
   
  
 0.447
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.445
luxS
S-ribosylhomocysteine lyase/ autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.431
Your Current Organism:
Melissococcus plutonius
NCBI taxonomy Id: 940190
Other names: M. plutonius ATCC 35311, Melissococcus plutonius ATCC 35311, Melissococcus plutonius NCDO 2443, Melissococcus plutonius str. ATCC 35311, Melissococcus plutonius strain ATCC 35311
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