STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPTP_1819Sensor histidine kinase. (97 aa)    
Predicted Functional Partners:
MPTP_1820
Sensor histidine kinase.
     0.974
MPTP_1818
Phosphate regulon transcriptional regulatory protein PhoB.
  
 
 0.896
secE
Preprotein translocase subunit SecE (TC 3.A.5.1.1); Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
 
     0.634
MPTP_1310
YycH protein.
 
  
 0.573
mprF-2
Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
   
 0.504
MPTP_1309
Hypothetical protein.
 
  
 0.483
MPTP_0793
Transcriptional regulator, TetR family.
  
   
 0.476
MPTP_0875
Conserved hypothetical protein.
  
     0.471
MPTP_0712
Two-component response regulator BceR.
  
 
 0.466
MPTP_1176
DNA-binding response regulator.
  
 
 0.466
Your Current Organism:
Melissococcus plutonius
NCBI taxonomy Id: 940190
Other names: M. plutonius ATCC 35311, Melissococcus plutonius ATCC 35311, Melissococcus plutonius NCDO 2443, Melissococcus plutonius str. ATCC 35311, Melissococcus plutonius strain ATCC 35311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.