STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC46A1Proton-coupled folate transporter. (453 aa)    
Predicted Functional Partners:
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
    0.773
SLC19A1
Folate transporter 1.
      
 0.723
MFSD10
Major facilitator superfamily domain-containing protein 10.
   
  
 0.723
L5KDZ4_PTEAL
Equilibrative nucleoside transporter 3.
      
 0.717
SLC29A2
Equilibrative nucleoside transporter 2.
      
 0.531
SLC36A1
Proton-coupled amino acid transporter 1.
   
  
 0.522
PIF1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]
   
  
 0.513
TMEM8B
Transmembrane protein 8B.
      
 0.507
TELO2
Telomere length regulation protein TEL2 like protein.
      
 0.507
L5K494_PTEAL
Solute carrier family 12 member 6.
    
 
 0.504
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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