STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (576 aa)    
Predicted Functional Partners:
GRK2
Beta-adrenergic receptor kinase 1.
     
0.928
L5L1S3_PTEAL
High affinity interleukin-8 receptor B; Belongs to the G-protein coupled receptor 1 family.
    
 0.918
OPRM1
Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.915
L5KHA6_PTEAL
C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.
    
  0.912
GRK4
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
  
  
 
0.901
ARRB1
Beta-arrestin-1.
   
 0.864
ARRB2
Beta-arrestin-2.
   
 0.864
XCR1
Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
  0.735
CCR7
C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.
    
 0.709
RHO
Rhodopsin.
   
 0.708
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.