STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (123 aa)    
Predicted Functional Partners:
L5JVM4_PTEAL
Interleukin-13.
   
  
 0.999
L5KFG2_PTEAL
T-cell surface glycoprotein CD4.
      
 0.999
IL10
Interleukin-10.
      
 0.976
IL5RA
Interleukin-5 receptor subunit alpha.
   
 0.940
IL6
Interleukin-6.
      
 0.914
IL4
Interleukin-4.
   
  
 0.901
CSF2
Granulocyte-macrophage colony-stimulating factor.
   
 
 0.870
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.
   
 
 0.857
L5JUB3_PTEAL
Interleukin-9.
   
  
 0.842
IL17A
Interleukin-17A.
   
  
 0.829
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.