STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (428 aa)    
Predicted Functional Partners:
L5JZ46_PTEAL
Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas.
    
 0.946
L5K1Y9_PTEAL
Pituitary adenylate cyclase-activating polypeptide.
    
 0.815
GHRH
Somatoliberin.
    
 0.757
L5KR83_PTEAL
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
      
 0.719
RAMP1
Receptor activity-modifying protein 1.
    
 0.619
CRH
Corticoliberin.
    
 0.598
PTH2
Tuberoinfundibular peptide of 39 residues.
    
 0.567
UCN
Urocortin.
    
 0.542
NGF
Beta-nerve growth factor; Belongs to the NGF-beta family.
      
 0.523
SLC1A7
Amino acid transporter.
      
 0.516
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.