STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L5K2T3_PTEALHistone H3; Belongs to the histone H3 family. (136 aa)    
Predicted Functional Partners:
L5JWL7_PTEAL
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.995
HAT1
Histone acetyltransferase type B catalytic subunit.
   
 0.952
ASF1A
Histone chaperone ASF1.
   
 
 0.886
WDR5
WD repeat-containing protein 5.
   
 0.851
L5L6H9_PTEAL
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.846
NASP
Nuclear autoantigenic sperm protein.
   
 
 0.835
L5JXP1_PTEAL
Lysine-specific demethylase 6B.
   
 0.805
L5K6Z2_PTEAL
Lysine-specific demethylase 6A.
   
 0.805
L5K9W5_PTEAL
Histone demethylase UTY.
   
 0.805
KDM6A
Lysine-specific demethylase 6A.
   
 0.805
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.