STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGNCingulin. (499 aa)    
Predicted Functional Partners:
ARHGEF18
Rho guanine nucleotide exchange factor 18.
     
 0.942
GATA4
Transcription factor GATA-4.
     
 0.901
L5K5J7_PTEAL
Cingulin.
 
     0.900
SYMPK
Symplekin.
      
 0.788
OCLN
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.
    
 0.732
L5L0E4_PTEAL
Tight junction protein ZO-1.
   
 0.676
L5L0U4_PTEAL
Tight junction protein ZO-1.
   
 0.676
CLDN2
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.643
F11R
Junctional adhesion molecule A.
   
 
 0.636
L5L6P9_PTEAL
Tight junction protein ZO-3; Belongs to the MAGUK family.
   
 0.631
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.