STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORCS2VPS10 domain-containing receptor SorCS2. (116 aa)    
Predicted Functional Partners:
NGF
Beta-nerve growth factor; Belongs to the NGF-beta family.
    
 
 0.759
GAK
Cyclin G-associated kinase.
     
 0.754
L5K5V2_PTEAL
Sortilin.
    
 
 0.595
L5K5B2_PTEAL
SH3 domain and tetratricopeptide repeat-containing protein 1.
      
 0.531
NTS
Neurotensin/neuromedin N.
    
 
 0.512
DNAJC6
Putative tyrosine-protein phosphatase auxilin.
     
 0.510
ST6GALNAC3
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Belongs to the glycosyltransferase 29 family.
      
 0.510
HIVEP2
Transcription factor HIVEP2.
    
 
 0.481
BDNF
Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
    
 
 0.472
L5K7U0_PTEAL
Synaptoporin.
  
    0.457
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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