STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSOCathepsin O; Belongs to the peptidase C1 family. (322 aa)    
Predicted Functional Partners:
BID
BH3-interacting domain death agonist.
   
 
 0.901
BCL2L1
Bcl-2-like protein 1.
     
 0.901
BCL2
Apoptosis regulator Bcl-2.
     
 0.901
RBM46
Putative RNA-binding protein 46.
   
  
 0.720
KCNJ10
ATP-sensitive inward rectifier potassium channel 10.
      
 0.692
BIRC5
Baculoviral IAP repeat-containing protein 5.
     
 0.659
L5KYH3_PTEAL
Baculoviral IAP repeat-containing protein 3.
     
 0.659
GUCY1B1
Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
      
 0.632
GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1.
      
 0.616
L5JQC4_PTEAL
Legumain.
   
 
 0.595
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.