STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L5KD67_PTEALSacsin. (3445 aa)    
Predicted Functional Partners:
L5KQ73_PTEAL
Inner centromere protein.
   
 0.713
CDCA8
Borealin.
   
 0.705
L5L134_PTEAL
E3 ubiquitin-protein ligase RNF216.
    
 0.689
DIABLO
Diablo like protein, mitochondrial.
    
 0.680
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
   
 0.652
OTUD4
OTU domain-containing protein 4.
   
 
 0.649
AURKB
Serine/threonine-protein kinase 12; Belongs to the protein kinase superfamily.
   
 0.624
AURKA
Serine/threonine-protein kinase 6.
   
 0.624
AURKC
Serine/threonine-protein kinase 13; Belongs to the protein kinase superfamily.
   
 0.624
GAN
Gigaxonin.
    
 
 0.592
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.