STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNCAIPSynphilin-1. (948 aa)    
Predicted Functional Partners:
PRKN
RBR-type E3 ubiquitin transferase.
    
 0.979
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 0.943
L5KF67_PTEAL
E3 ubiquitin-protein ligase parkin.
    
 0.803
SH3BP5L
SH3 domain-binding protein 5-like protein.
    
 
 0.793
CLSTN3
Calsyntenin-3.
    
 0.720
TELO2
Telomere length regulation protein TEL2 like protein.
    
 
 0.719
SNCG
Gamma-synuclein; Belongs to the synuclein family.
    
 0.674
NUB1
NEDD8 ultimate buster 1.
    
 0.618
FAM170A
Protein FAM170A.
    
 
 0.616
SIAH1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.608
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.