STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTN2Reticulon. (466 aa)    
Predicted Functional Partners:
ATL1
Atlastin-1.
    
 
 0.756
SPAST
Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]
   
 
 0.701
ATL2
Atlastin-2.
    
 
 0.687
ATL3
Atlastin-3.
    
 
 0.685
REEP5
Receptor expression-enhancing protein.
   
 
 0.584
REEP2
Receptor expression-enhancing protein.
   
 
 0.581
DNAJB12
DnaJ like protein subfamily B member 12.
   
 
 0.566
L5KM98_PTEAL
Beta-secretase 1.
   
 
 0.564
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
   
 
 0.564
REEP6
Receptor expression-enhancing protein.
    
 
 0.558
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.