STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L5L0J8_PTEALTreacle protein. (1546 aa)    
Predicted Functional Partners:
L5JW46_PTEAL
Nucleolar protein 56.
  
 
 
 0.542
EMG1
Putative ribosome biogenesis protein NEP1.
   
  
 0.526
KBTBD8
Kelch repeat and BTB domain-containing protein 8.
    
 0.520
L5JVV3_PTEAL
Protein SSX6.
      
 0.501
WDR36
WD repeat-containing protein 36.
      
 0.501
UTP18
U3 small nucleolar RNA-associated protein 18 like protein.
    
 
 0.488
CAPZA2
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.481
CCDC86
Coiled-coil domain-containing protein 86.
   
  
 0.476
RIOK2
Serine/threonine-protein kinase RIO2.
    
 
 0.469
PAFAH1B1
Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]
    
 0.457
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.