STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L5L582_PTEALCaspase recruitment domain-containing protein 8. (145 aa)    
Predicted Functional Partners:
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.711
DPP9
Dipeptidyl peptidase 9; Belongs to the peptidase S9B family.
    
 
 0.638
BIRC6
Baculoviral IAP repeat-containing protein 6.
   
 0.615
APPL1
DCC-interacting protein 13-alpha.
    
 0.601
L5KG53_PTEAL
DCC-interacting protein 13-beta.
    
 0.601
APPL2
DCC-interacting protein 13-beta.
    
 0.601
L5L4D1_PTEAL
Caspase recruitment domain-containing protein 8.
  
     0.523
L5L771_PTEAL
E3 ubiquitin-protein ligase MIB2.
    
 0.492
L5KK19_PTEAL
Gasdermin-D.
    
 0.478
DPP8
Dipeptidyl peptidase 8; Belongs to the peptidase S9B family.
    
 
 0.469
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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